Alemtuzumab: precautions

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Alemtuzumab: precautions. Co-trimoxazole 960mg three times a week for one month after each cycle. Fully referenced neurology checklist.

Listeria prophylaxis: options

  • Co-trimoxazole 960mg three times a week for one month after each cycle
  • Amoxicillin 1g tid or Co-trimoxazole 960mg bid for four days before each cycle

Lifestyle precautions

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Other precautions

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References

  1. Association of British Neurologists. Guidance on the prevention of Listeria infection after alemtuzumab treatment of multiple sclerosis. Accessed 25/07/2017.
  2. Barclay K, Carruthers R, Traboulsee A, et al. Best practices for long-term monitoring and follow-up of alemtuzumab-treated MS patients in real-world clinical settings. Front Neurol 2019; 10:253. 
  3. Alroughani R, Altintas A, Al Jumah M, et al. Pregnancy and the use of disease-modifying therapies in patients with multiple sclerosis: benefits versus risks. Mult Scler Int 2016; 2016:1034912.

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