Anti MGluR antibody syndromes
Evidence-based neurology checklist on anti mglur antibody syndromes: Anti-MGluR1 antibody syndrome This may be paraneoplastic It presents as a subacute cerebellar syndrome Associated features The MRI may show cerebellar atrophy It may result in long-term disability Anti-MGluR2 antibody syndrome…
Anti-MGluR1 antibody syndrome
- This may be paraneoplastic
- It presents as a subacute cerebellar syndrome
- Associated features
- The MRI may show cerebellar atrophy
- It may result in long-term disability
Anti-MGluR2 antibody syndrome
Anti-MGluR5 antibody syndrome
Synonym
References
- Jarius S, Wildemann B. 'Medusa-head ataxia': the expanding spectrum of Purkinje cell antibodies in autoimmune cerebellar ataxia. Part 1: Anti-mGluR1, anti-Homer-3, anti-Sj/ITPR1 and anti-CARP VIII. J Neuroinflammation 2015; 12:166.
- Lopez-Chiriboga AS, Komorowski L, Kümpfel T, et al. Metabotropic glutamate receptor type 1 autoimmunity: Clinical features and treatment outcomes. Neurology 2016; 86:1009-1013.
- Marignier R, Chenevier F, Rogemond V, et al. Metabotropic glutamate receptor type 1 autoantibody-associated cerebellitis: a primary autoimmune disease? Arch Neurol 2010; 67:627-630.
- Spatola M, Petit Pedrol M, Maudes E et al. Clinical features, prognostic factors, and antibody effects in anti-mGluR1 encephalitis. Neurology 2020; 95:e3012-e3025.
- Iorio R, Damato V, Mirabella M, Vita MG, et al. Cerebellar degeneration associated with mGluR1 autoantibodies as a paraneoplastic manifestation of prostate adenocarcinoma. J Neuroimmunol 2013; 263:155-158.
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