Arachnoid cysts: pathology and classifications

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Arachnoid cysts: pathology and classifications. These are congenital fluid-filled malformations. Fully referenced neurology checklist.

Pathology

  • These are congenital fluid-filled malformations
  • The arachnoid membrane is split
  • There is thick collagen in the cyst wall
  • There are hyperplastic arachnoid cells in the cyst wall
  • There are no traversing trabecular processes in the cyst

Genetic transmission of familial types

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Frequent locations

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Other locations

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Classification of middle cranial fossa cysts (Galassi classification)

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Classification of cerebellopontine angle/ cysts

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Classification of posterior fossa cysts

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Radiological features

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References

  1. Ahmed AK, Cohen AR. Intracranial arachnoid cysts. Childs Nerv Syst 2023 (Online ahead of print).
  2. Furey CG, Timberlake AT, Nelson-Williams C, et al. Xp22.2 chromosomal duplication in familial intracranial arachnoid cyst. JAMA Neurol 2017; 74:1503-1504.
  3. Bayrakli F, Okten AI, Kartal U, et al. Intracranial arachnoid cyst family with autosomal recessive trait mapped to chromosome 6q22.31-23.2. Acta Neurochir (Wien) 2012; 154:1287-1292. 
  4. Ibrahim GM, Alotaibi NM, Lipsman N, Nassiri F, da Costa L. De novo formation of a symptomatic arachnoid cyst in an adult. Neurology 2017; 88:331-332. 
  5. Pradilla G, Jallo G. Arachnoid cysts: case series and review of the literature. Neurosurg Focus 2007; 22:E7.
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