Arsenic induced peripheral neuropathy (PN)
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Arsenic induced peripheral neuropathy (PN). Occupational exposure, Contaminated underground water. Fully referenced neurology checklist.
Sources of poisoning
- Occupational exposure
- Contaminated underground water
- Contaminated seafood and animal products
- Crops irrigated with contaminated water
Neurological features
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Dermatological features
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Systemic features
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Nerve conduction studies (NCS)
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Electromyogram (EMG)
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Other investigations
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Treatment: chelating agents
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References
- Oh SJ. Electrophysiological profile in arsenic neuropathy. JNNP 1991; 54:1103-1105.
- Ropper AH, Brown RH. Principles of Neurology Eighth edition. McGraw Hill New York 2005 p1132.
- Othman L, Nafadi A, Alkhalid SH, Mazraani N. Arsenic poisoning due to high consumption of canned sardines in Jeddah, Saudi Arabia. Cureus 2021; 13:e12780.
- Carvalho Neto EG, Damiani Monteiro M, Rieder CRM. Teaching NeuroImage: Mees lines as a clinical clue to arsenic poisoning. Neurology 2026; 107:e218552.
- Valappil AV, Mammen A. Subacute arsenic neuropathy: clinical and electrophysiological observations. J Neurosci Rural Pract 2019; 10:529-532.