Arsenic induced peripheral neuropathy (PN)

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Arsenic induced peripheral neuropathy (PN). Occupational exposure, Contaminated underground water. Fully referenced neurology checklist.

Sources of poisoning

  • Occupational exposure
  • Contaminated underground water
  • Contaminated seafood and animal products
  • Crops irrigated with contaminated water

Neurological features

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Dermatological features

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Systemic features

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Nerve conduction studies (NCS)

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Electromyogram (EMG)

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Other investigations

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Treatment: chelating agents

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References

  1. Oh SJ. Electrophysiological profile in arsenic neuropathy. JNNP 1991; 54:1103-1105.
  2. Ropper AH, Brown RH. Principles of Neurology Eighth edition. McGraw Hill New York 2005 p1132.
  3. Othman L, Nafadi A, Alkhalid SH, Mazraani N. Arsenic poisoning due to high consumption of canned sardines in Jeddah, Saudi Arabia. Cureus 2021; 13:e12780.
  4. Carvalho Neto EG, Damiani Monteiro M, Rieder CRM. Teaching NeuroImage: Mees lines as a clinical clue to arsenic poisoning. Neurology 2026; 107:e218552.
  5. Valappil AV, Mammen A. Subacute arsenic neuropathy: clinical and electrophysiological observations. J Neurosci Rural Pract 2019; 10:529-532.

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