Behavioural variant frontotemporal dementia (bvFTD): features

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Behavioural variant frontotemporal dementia (bvFTD): features. Inappropriate or offensive speech. Fully referenced neurology checklist.

Features of disinhibition

  • Inappropriate or offensive speech
  • Public urination and masturbation
  • Restlessness, impulsivity and irritability
  • Pressured speech
  • Aggressiveness
  • Violent outbursts
  • Excessive sentimentality
  • Theft and assault

Other behavioural abnormalities

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Motor stereotypy

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Repetitive activities

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Features associated with C9orf72 gene mutation

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Neuropsychiatric features

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Environmental dependency: types

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Other features

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Poor prognostic factors

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References

  1. Rabinovici GD, Miller BL. Frontotemporal lobar degeneration: epidemiology, pathophysiology, diagnosis and management. CNS Drugs 2010; 24:375-398.
  2. Seelar H, Rohrer JD, Pijnenburg AL, Fox NC, van Swieten JC. Clinical, genetic and pathological heterogeneity of frontotemporal dementia: a review. JNNP 2011; 82:476-486.
  3. Neary D, Snowden J, Mann D. Frontotemporal dementia. Lancet Neurol 2005; 4:771-780.
  4. Boxer AL, Boeve BF. Frontotemporal dementia treatment: current symptomatic therapies and implications of recent genetic, biochemical, and neuroimaging studies. Alzheimer Dis Assoc Disord 2007; 21:S79-S87.
  5. Rosen HJ, Lengenfelder J, Miller B. Frontotemporal dementia. Neurol Clin. 2000; 18:979–992. 
  6. And 16 more. Subscribe to see the full list

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