Cerebral aneurysms: non-aneurysm related risk factors for rupture
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Cerebral aneurysms: non-aneurysm related risk factors for rupture. Older age, Female gender, Non-Caucasian ethnicity. Fully referenced neurology checklist.
Patient-related risk factors
- Older age
- Female gender
- Non-Caucasian ethnicity
- Low body weight
- Within 5 years of aneurysm formation
- History of previous subarachnoid haemorrhage (SAH)
- Change in character of headaches in the preceding 3 months
- Occupational physical activity
Medical co-morbidities
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Recreational risk factors
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Uncertain risk: medications
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Possible protective factors against rupture
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References
- Clarke M. Systematic review of reviews of risk factors for intracranial aneurysms. Neuroradiology 2008; 50:653-664.
- Thompson BG, Brown RD Jr, Amin-Hanjani S, et al. American Heart Association Stroke Council, Council on Cardiovascular and Stroke Nursing, and Council on Epidemiology and Prevention; American Heart Association; American Stroke Association. Guidelines for the management of patients with unruptured intracranial aneurysms: a guideline for healthcare professionals from the American Heart Association/American Stroke Association. Stroke 2015; 46:2368-2400.
- Juvela S, Poussa K, Lehto H, Porras M. Natural history of unruptured intracranial aneurysms: a long-term follow-up study. Stroke 2013; 44:2414-2421.
- Ishibashi T, Murayama Y, Urashima M, Saguchi T, Ebara M, Arakawa H, Irie K, Takao H, Abe T. Unruptured intracranial aneurysms: incidence of rupture and risk factors. Stroke 2009; 40:313-316.
- Mitchell P, Gholkar A, Vindlacheruvu RR, Mendelow AD. Unruptured intracranial aneurysms: benign curiosity or ticking bomb? Lancet Neurol 2004; 3:85-92.
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