Cerebral cavernous malformations (cavernomas): bleeding risk
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Cerebral cavernous malformations (cavernomas): bleeding risk. The risk is 8% for asymptomatic brainstem cavernomas. Fully referenced neurology checklist.
5-year haemorrhage risk
- The risk is 8% for asymptomatic brainstem cavernomas
- The risk is 4% for asymptomatic non-brainstem cavernomas
Subject-related bleeding risk factors
Locked: subscribe to see this section.
Cavernoma-related bleeding risk factors
Locked: subscribe to see this section.
Factors that reduce the risk of haemorrhage
Locked: subscribe to see this section.
Factors that do not increase the risk of haemorrhage
Locked: subscribe to see this section.
References
- Petersen TA, Morrison LA, Schrader RM, Hart BL. Familial versus sporadic cavernous malformations: differences in developmental venous anomaly association and lesion phenotype. Am J Neuroradiol 2010; 31:377–382.
- Horne MA, Flemming KD, Su IC, et al; Cerebral Cavernous Malformations Individual Patient Data Meta-analysis Collaborators. Clinical course of untreated cerebral cavernous malformations: a meta-analysis of individual patient data. Lancet Neurol 2015; 15:166-173.
- Kuroedov D, Cunha B, Pamplona J, Castillo M, Ramalho J. Cerebral cavernous malformations: typical and atypical imaging characteristics. J Neuroimaging 2022 (Online ahead of print).
- Fleming KD, Limk MJ, Christianson TJH, et al. Prospective hemorrhage risk of intracerebral cavernous malformations. Neurology 2012; 78:632-636.
- Kashefiolasl S, Bruder M, Brawanski N, et al. A benchmark approach to hemorrhage risk management of cavernous malformations. Neurology 2018; 90:e856-e863.
- And 7 more. Subscribe to see the full list
