Cerebral cavernous malformations (cavernomas): surgical excision

Evidence-based neurology checklist on cerebral cavernous malformations (cavernomas): surgical excision: Indications Superficial lesions Overt bleeding Accessible non-eloquent areas Progressive enlargement with mass effect Accessible single lesion with seizures: especially temporal lobe Indications…

Indications

  • Superficial lesions
  • Overt bleeding
  • Accessible non-eloquent areas
  • Progressive enlargement with mass effect
  • Accessible single lesion with seizures: especially temporal lobe

Indications for asymptomatic brain lesions

Indications for symptomatic brain lesions

Indications for brainstem lesions

Indications for spinal lesions

Surgical resection (microsurgery) of spinal cavernomas

References

  1. Akers AL, Albanese J, Alcazar-Felix RJ, et al. Guidelines for the diagnosis and clinical management of cavernous malformations of the brain and spinal cord: consensus recommendations based on a systematic literature review by the Alliance to Cure Cavernous Malformation Clinical Advisory Board Experts Panel. Neurosurgery 2026; 98:3-22.
  2. Akers A, Al-Shahi Salman R, A Awad I, et al. Synopsis of guidelines for the clinical management of cerebral cavernous malformations: consensus recommendations based on systematic literature review by the Angioma Alliance Scientific Advisory Board Clinical Experts Panel. Neurosurgery 2017; 80:665-680.
  3. Bian LG, Bertalanffy H, Sun QF, Shen JK. Intramedullary cavernous malformations: clinical features and surgical technique via hemilaminectomy. Clin Neurol Neurosurg 2009; 111:511-517. 
  4. Reitz M, Burkhardt T, Vettorazzi E, et al. Intramedullary spinal cavernoma: clinical presentation, microsurgical approach, and long-term outcome in a cohort of 48 patients. Neurosurg Focus 2015; 39:E19. 
  5. Labauge P, Bouly S, Parker F, et al; French Study Group of Spinal Cord Cavernomas. Outcome in 53 patients with spinal cord cavernomas. Surg Neurol 2008; 70:176-181.
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