Chronic immune sensory polyradiculopathy (CISP)

Evidence-based neurology checklist on chronic immune sensory polyradiculopathy (cisp): Pathology This is a restricted form of CIDP It preferentially affects large myelinated posterior root fibers Clinical features Neurophysiology Cerebrospinal fluid (CSF) analysis Sensory rootlet biopsy: features…

Pathology

  • This is a restricted form of CIDP
  • It preferentially affects large myelinated posterior root fibers

Clinical features

Neurophysiology

Cerebrospinal fluid (CSF) analysis

Sensory rootlet biopsy: features

Magnetic resonance imaging (MRI): features

Treatment

References

  1. Sinnreich M, Klein CJ, Daube JR, Engelstad J, Spinner RJ, Dyck PJ. Chronic immune sensory polyradiculopathy: a possibly treatable sensory ataxia. Neurology 2004; 63:1662-1669.
  2. Trip SA, Saifee T, Honan W, et al. Chronic immune sensory polyradiculopathy with cranial and peripheral nerve involvement. J Neurol 2012; 259:1238-1240.
  3. Clerici AM, Nobile-Orazio E, Mauri M, Squellati FS, Bono GG. Utility of somatosensory evoked potentials in the assessment of response to IVIG in a long-lasting case of chronic immune sensory polyradiculopathy. BMC Neurol 2017; 17:127.
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