CIDP treatment: immunosuppressants

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

CIDP treatment: immunosuppressants. These are first line treatments if there are no contraindications. Fully referenced neurology checklist.

Steroids: benefits

  • These are first line treatments if there are no contraindications
  • They provide long term remission in a quarter of patients

Steroids: options

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Rituximab

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Treatments with poor evidence

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Treatments to be avoided

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Investigational treatments

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Scoring systems

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Monitoring

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Acronym

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References

  1. Ripellino P, Fleetwood T, Cantello R, Comi C. Treatment of chronic inflammatory demyelinating polyneuropathy: from molecular bases to practical considerations. Autoimmune Dis 2014; 2014:201657.
  2. Eftimov F, Vermeulen M, van Doorn PA, et al. Long-term remission of CIDP after pulsed dexamethasone or short-term prednisone treatment. Neurology 2012; 78:1079-1084.
  3. van Schaik IN, Eftimov F, van Doorn PA, et al. Pulsed high-dose dexamethasone versus standard prednisolone treatment for chronic inflammatory demyelinating polyradiculoneuropathy (PREDICT study): a double-blind, randomised, controlled trial. Lancet Neurol 2010; 9:245-253.
  4. Kuitwaard K, Hahn AF, Vermeulen M, Venance SL, van Doorn PA. Intravenous immunoglobulin response in treatment-naïve chronic inflammatory demyelinating polyradiculoneuropathy. JNNP 2015; 86:1331-1336.
  5. Van den Bergh PYK, van Doorn PA, Hadden RDM, et al. European Academy of Neurology/Peripheral Nerve Society guideline on diagnosis and treatment of chronic inflammatory demyelinating polyradiculoneuropathy: Report of a joint Task Force-Second revision. Eur J Neurol 2021 (Online ahead of print).
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