Cramps fasciculation syndrome (CFS)

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Cramps fasciculation syndrome (CFS). Myalgia, Cramps, Muscle stiffness, Muscle twitching, Exercise intolerance. Fully referenced neurology checklist.

Clinical features

  • Myalgia
  • Cramps
  • Muscle stiffness
  • Muscle twitching
  • Exercise intolerance
  • Peripheral nerve hyper excitability
  • Dysphagia reported
  • Monofocal motor neuropathy: case report

Blood tests

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Neurophysiology: positive features

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Neurophysiology: absent features

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Outcome

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Treatment

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References

  1. Tahmoush AJ, Alonso RJ, Tahmoush JP, et al. Cramp-fasciculation syndrome: a treatable hyperexcitability peripheral nerve disorder. Neurology 1991; 41:1021-1024.
  2. Ropper AH, Brown RH. Principles of Neurology. Eighth edition. McGraw Hill New York 2005 p1278.
  3. Braune S, Hentschel M, Glocker FX, Lücking CH. Involvement of the esophagus in the cramp-fasciculation syndrome. Muscle Nerve 1998; 21:802-804.
  4. Dubuisson NJ, Van Pesch V, Van den Bergh PY. Cramp-fasciculation syndrome associated with monofocal motor neuropathy. Muscle Nerve 2017; 56:828-832:.
  5. Harrison TB, Benatar M. Accuracy of repetitive nerve stimulation for diagnosis of the cramp-fasciculation syndrome. Muscle Nerve 2007; 35:776-780.
  6. And 4 more. Subscribe to see the full list

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