Dermatomyositis: clinical features

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Dermatomyositis: clinical features. Exposure to ultraviolet light, TIF1 gene mutations, Some class 2 HLA alleles. Fully referenced neurology checklist.

Possible risk factors

  • Exposure to ultraviolet light
  • TIF1 gene mutations
  • Some class 2 HLA alleles

Major dermatological features

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Other dermatological features

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Neurological features

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Oral features

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Anti-MDA5 features

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Associated disorders

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References

  1. Dalakas MC. Therapeutic advances and future prospects in immune-mediated inflammatory myopathies. Ther Adv Neurol Disord 2008; 1:157-166.
  2. Mammen AL. Dermatomyositis and polymyositis: Clinical presentation, autoantibodies, and pathogenesis. Ann N Y Acad Sci 2010; 1184:134-153.
  3. Amato AA, Barohn RJ. Evaluation and treatment of inflammatory myopathies. JNNP 2009; 80:1060-1068.
  4. Selva-O'Callaghan A, Pinal-Fernandez I, Trallero-Araguás E, Milisenda JC, Grau-Junyent JM, Mammen AL. Classification and management of adult inflammatory myopathies. Lancet Neurol 2018; 17:816-828. 
  5. Marvi U, Chung L, Fiorentino D. Clinical presentation and evaluation of dermatomyositis. Indian J Dermatol 2012; 57:375-381.
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