Embolic stroke of undetermined source (ESUS): management

Evidence-based neurology checklist on embolic stroke of undetermined source (esus): management: Neurological investigations Brain imaging: CT or MRI Catheter, MR or CT angiography: intracranial and extracranial Transcranial Doppler ultrasound Echocardiogram Cardiovascular MRI Troponin Other…

Neurological investigations

  • Brain imaging: CT or MRI
  • Catheter, MR or CT angiography: intracranial and extracranial
  • Transcranial Doppler ultrasound

Echocardiogram

Cardiovascular MRI

Troponin

Other cardiac investigations

Treatment: Aspirin

Treatment: new oral anticoagulants (NOACs)

References

  1. Hart RG, Diener HC, Coutts SB, et al; Cryptogenic Stroke/ESUS International Working Group. Embolic strokes of undetermined source: the case for a new clinical construct. Lancet Neurol 2014; 13:429-438.
  2. de Bruijn SF, Agema WR, Lammers GJ, et al. Transesophageal echocardiography is superior to transthoracic echocardiography in management of patients of any age with transient ischemic attack or stroke. Stroke 2006; 37:2531-2534.
  3. Walpot J, Pasteuning WH, Hoevenaar M, et al. Transesophageal echocardiography in patients with cryptogenic stroke: does it alter their management? A 3-year retrospective study in a single non-referral centre. Acta Clin Belg 2006; 61:243-248.
  4. Blum A, Reisner S, Farbstein Y. Transesophageal echocardiography (TEE) vs. transthoracic echocardiography (TTE) in assessing cardio-vascular sources of emboli in patients with acute ischemic stroke. Med Sci Monit 2004; 10:CR521-CR523.
  5. Katsanos AH, Bhole R, Frogoudaki A, et al. The value of transesophageal echocardiography for embolic strokes of undetermined source. Neurology 2016; 87:988-995.
  6. And 11 more. Subscribe to see the full list

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