Essential tremor (ET): drug treatment

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Essential tremor (ET): drug treatment. Propranolol, Primidone. Fully referenced neurology checklist.

Level A: established effective

  • Propranolol
  • Primidone

Level B: probably effective

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Level C: possibly effective

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Level U: insufficient evidence

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Ineffective

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Recent reports

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Absolute contraindications to beta blockers

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Relative contraindications to beta blockers

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References

  1. Zesiewicz TA, Elble RJ, Louis ED, et al. Evidence-based guideline update: treatment of essential tremor. Report of the Quality Standards Subcommittee of the American Academy of Neurology. Neurology 2011; 77:1752-1755.
  2. Deuschl G, Raethjen J, Hellriegel H, Elbe R. Treatment of patients with essential tremor. Lancet Neurol 2011; 10:148-161.
  3. Ferreira JJ, Mestre TA, Lyons KE, et al; MDS Task Force on Tremor and the MDS Evidence Based Medicine Committee. MDS evidence-based review of treatments for essential tremor. Mov Disord 2019; 34:950-958.
  4. Dash D, Bruno V, Schwingenschuh P, et al. Update on medical treatments for essential tremor: an International Parkinson and Movement Disorder Society Evidence-Based Medicine Review. Mov Disord 2026; 41:815-825.
  5. Abboud H, Ahmed A, Fernandez HH. Essential tremor: choosing the right management plan for your patient. Cleve Clin J Med 2011; 78:821-828.

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