Granulomatosis with polyangiitis (GPA): systemic features

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Granulomatosis with polyangiitis (GPA): systemic features. This is a necrotising granulomatous vasculitis of small vessels.

Pathology

  • This is a necrotising granulomatous vasculitis of small vessels
  • It is an ANCA positive vasculitis

Renal features

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Respiratory features

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ENT features

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Cardiac features

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Gastrointestinal and dental features

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Ophthalmic features

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Retinal features

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Dermatological features

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Genitourinary features

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Other features

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Differential diagnosis

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Synonym

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References

  1. Esposito D, Trimpou P, Giugliano D, Dehlin M, Ragnarsson O. Pituitary dysfunction in granulomatosis with polyangiitis. Pituitary 2017; 20:594-601.
  2. Grotz W, Wanner C, Keller E, et al. Crescentic glomerulonephritis in Wegener's granulomatosis: morphology, therapy, outcome. Clin Nephrol 1991; 35:243-251.
  3. Jung JH, Ahn SH. Granulomatosis with polyangiitis presenting as cholangitis and acute kidney injury. Chonnam Med J 2019; 55:124-125.
  4. Roussou M, Dimopoulos SK, Dimopoulos MA, Anastasiou-Nana MI. Wegener's granulomatosis presenting as a renal mass. Urology 2008; 71:547.e1-e2.
  5. Farpour F, Abrudescu A. A case of granulomatosis with polyangiitis causing hydroureter and hydronephrosis. Case Rep Rheumatol 2014; 2014:713957.
  6. And 50 more. Subscribe to see the full list

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