Hereditary spastic paraplegia type 19 (SPG19)

Evidence-based neurology checklist on hereditary spastic paraplegia type 19 (spg19): Genetics This is caused by mutations in chromosome 9q The transmission is autosomal dominant The onset is late It causes a mild HSP phenotype Clinical features Nerve conduction studies (NCS)

Genetics

  • This is caused by mutations in chromosome 9q
  • The transmission is autosomal dominant
  • The onset is late
  • It causes a mild HSP phenotype

Clinical features

Nerve conduction studies (NCS)

References

  1. Valente EM, Brancati F, Caputo V, et al. Novel locus for autosomal dominant pure hereditary spastic paraplegia (SPG19) maps to chromosome 9q33-q34. Ann Neurol 2002; 51:681-685. 
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