Hereditary spastic paraplegia type 32 (SPG32)

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Hereditary spastic paraplegia type 32 (SPG32). This is caused by mutations in chromosome 14q. Fully referenced neurology checklist.

Genetics

  • This is caused by mutations in chromosome 14q
  • The transmission is autosomal recessive

Clinical features

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Magnetic resonance imaging (MRI) brain: features

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References

  1. Stevanin G, Paternotte C, Coutinho P, et al. A new locus for autosomal recessive spastic paraplegia (SPG32) on chromosome 14q12-q21. Neurology 2007; 68:1837-1840. 

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