Intracerebral haemorrhage (ICH): causes and risk factors

Evidence-based neurology checklist on intracerebral haemorrhage (ich): causes and risk factors: Vascular causes Hypertension Cerebral amyloid angiopathy (CAA) CAA-Related Inflammation Amyloid-β–Related Angiitis Arteriovenous malformation (AVM) Cerebral aneurysm Cavernous malformation (cavernoma)…

Vascular causes

  • Hypertension
  • Cerebral amyloid angiopathy (CAA)
  • CAA-Related Inflammation
  • Amyloid-β–Related Angiitis
  • Arteriovenous malformation (AVM)
  • Cerebral aneurysm
  • Cavernous malformation (cavernoma)
  • Cerebral vein thrombosis (CVT)
  • Dural arteriovenous fistula (dAVF)
  • Vasculitis
  • Small vessel disease (SVD)
  • Carotid-cavernous fistula
  • Reversible Cerebral Vasoconstriction Syndrome (RCVS)
  • Posterior Reversible Encephalopathy Syndrome (PRES)
  • Moyamoya disease: due to secondary aneurysms
  • Sneddon syndrome

Congenital heart diseases

Oral anticoagulants: predictors

Malignant causes

Infections

Inflammatory

Genetic risk factors

Metabolic risk factors

Drugs and toxins

Clotting factor deficiencies

Other causes

References

  1. Al-Shahi Salman R, Labovitz DL, Stapf C. Spontaneous intracerebral haemorrhage. BMJ 2009; 349:b2586.
  2. Tartarin H, Morotti A, Van Etten ES, et al. Uncommon causes of nontraumatic intracerebral hemorrhage. Stroke 2024; 55:1416-1427.
  3. Walsh KB, Woo D, Sekar P, et al. Untreated hypertension: a powerful risk factor for lobar and nonlobar intracerebral hemorrhage in whites, blacks, and hispanics. Circulation 2016; 134:1444-1452. 
  4. d'Angelo VA, Monte V, Scialfa G, Fiumara E, Scotti G. Intracerebral venous hemorrhage in "high-risk" carotid-cavernous fistula. Surg Neurol 1988; 30:387-390.
  5. Bram R, Chaudhry N, Choi JL, Atwal G. Delayed intracerebral hemorrhage from a traumatic carotid-cavernous fistula associated with an enucleated orbit. J Cerebrovasc Endovasc Neurosurg 2021; 23:251-259. 
  6. And 31 more. Subscribe to see the full list

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