Intravenous immunoglobulins (IVIg): complications
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Intravenous immunoglobulins (IVIg): complications. Onset, Manifestations, Management. Fully referenced neurology checklist.
Thromboembolic stroke
- Onset
- Manifestations
- Management
Headache
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Aseptic meningitis
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Flu-like symptoms
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Gastrointestinal complications
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Cardiovascular complications
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Dermatological complications
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Vasomotor complications
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Other systemic complications
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Laboratory complications
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References
- Jiang M, Kimber JS, Gupta A, et al. Adverse reactions associated with intravenous immunoglobulin administration in the treatment of neurological disorders: a systematic review. Int Arch Allergy Immunol 2023; 184:513-528.
- Patwa HS, Chaudhry V, Katzberg H, et al. Evidence-based guideline: intravenous immunoglobulin in the treatment of neuromuscular disorders. Report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology. Neurology 2012; 78:1009-1015.
- Association of British Neurologists. Guidelines for the use of intravenous immunoglobulin in neurological diseases. Revised 2005.
- Kapoor M, Spillane J, Englezou C, et al. Thromboembolic risk with IVIg: incidence and risk factors in patients with inflammatory neuropathy. Neurology 2020; 94:e635-e638.
- Rogers T, White LM, Cooper S, Smith H, Gosal D, Keh RYS. Thromboembolic risk of intravenous and subcutaneous immunoglobulin treatment for neuroinflammatory diseases. JNNP 2026; 97:204-208.
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