Kleine-Levin syndrome (KLS): management

Evidence-based neurology checklist on kleine-levin syndrome (kls): management: Acute treatment Methylphenidate Amphetamines Pemoline-piracetam-meclofenoxate Neuroleptics Intravenous steroids: these may shorten the duration of episodes Prophylaxis Synonym

Acute treatment

  • Methylphenidate
  • Amphetamines
  • Pemoline-piracetam-meclofenoxate
  • Neuroleptics
  • Intravenous steroids: these may shorten the duration of episodes

Prophylaxis

Synonym

References

  1. Arnulf I, Zeitzer JM, File J, Farber N, Mignot E. Kleine-Levin syndrome: a systematic review of 186 cases in the literature. Brain 2005; 128:2763-2776.
  2. Dauvilliers Y, Mayer G, Lecendreux M, et al. Kleine-Levin syndrome: an autoimmune hypothesis based on clinical and genetic analysis. Neurology 2002; 59:1739-1745.
  3. Leu-Semenescu S, Le Corvec T, Groos E, Lavault S, Golmard JL, Arnulf I. Lithium therapy in Kleine-Levin syndrome: an open-label, controlled study in 130 patients. Neurology 2015; 85:1655-1662.
  4. Léotard A, Groos E, Chaumereuil C, et al. IV steroids during long episodes of Kleine-Levin syndrome. Neurology 2018; 90:e1488-e1492.
  5. Nebhinani N, Suthar N. Sleeping beauty syndrome: a case report and review of female cases reported from India. Indian J Psychol Med 2017; 39:357-360. 
  6. And 0 more. Subscribe to see the full list

Related checklists

Loading...