Krabbe disease: MRI features
Evidence-based neurology checklist on krabbe disease: mri features: Tigroid appearance This is caused by symmetrical T2 hyperintensities These are mainly periventricular: especially parieto-occipital They are also seen in the deep white matter They do not enhance with contrast Other abnormalities…
Tigroid appearance
- This is caused by symmetrical T2 hyperintensities
- These are mainly periventricular: especially parieto-occipital
- They are also seen in the deep white matter
- They do not enhance with contrast
Other abnormalities
Spared areas
Diffusion tension imaging (DTI) features
Differentials of parietal-occipital changes
Differentials of periventricular changes
Synonym
References
- Gelinas J, Liao P, Lehman A, Stockler S, Sirrs S. Krabbe disease: a potentially treatable white matter disorder. Neurology 2012; 79:e170-e172.
- Andriescu EC, Russo SN, Pérez CA. Teaching NeuroImages: Infantile-onset Krabbe disease with tigroid appearance of the white matter. Neurology 2020; 94: e1964-e1965.
- Given CA 2nd, Santos CC, Durden DD. Intracranial and spinal MR imaging findings associated with Krabbe's disease: case report. Am J Neuroradiol 2001; 22:1782-1785.
- Kapoor R, MCDonald WI, Crockard A, Moseley IF. Clinical onset and MRI features of Krabbe's disease in adolescence. JNNP 1992; 55:331-332.
- Bajaj NPS, Waldman A, Orrell R. Wood NW, Bhatia KP. Familial adult onset of Krabbe's disease resembling hereditary spastic paraplegia with normal imaging. JNNP 2002; 72:635-638.
- And 1 more. Subscribe to see the full list
