Lacunar strokes

Evidence-based neurology checklist on lacunar strokes: Characteristics These are deep infarcts < 20mm in diameter They result from occlusion of penetrating arteries They account for 25% of ischemic strokes They cause 25% of cortical syndromes They occur silently in a quarter of people >70 years…

Characteristics

  • These are deep infarcts < 20mm in diameter
  • They result from occlusion of penetrating arteries
  • They account for 25% of ischemic strokes
  • They cause 25% of cortical syndromes
  • They occur silently in a quarter of people >70 years
  • They increase the risk of stroke and dementia

Risk factors: non-genetic

Risk factors: genetic

Clinical syndromes

Typical presentation

Features not associated with lacunar stroke

Predictors of recurrence

Investigations

Treatment

References

  1. Yaghi S, Raz E, Yang D, et al. Lacunar stroke: mechanisms and therapeutic implications. JNNP 2021 (Online ahead of print).
  2. Rajapakse A, Rajapakse S, Sharma JC. Is investigating for carotid artery disease warranted in non-cortical lacunar infarction? Stroke 2011; 42:217-220.
  3. Norrving B. Lacunar infarcts: no black holes in the brain are benign. Pract Neurol 2008; 8:222-228.
  4. Sacco S, Marini C, Totaro R, Russo T, Cerone D, Carolei A. A population-based study of the incidence and prognosis of lacunar stroke. Neurology 2006; 66:1335-1338.
  5. Bezerra DC, Sharret AR, Matsushita K, et al. Risk factors for lacune subtypes in the Artherosclerosis in Communities (ARIC) Study. Neurology 2012; 78:102-108.
  6. And 8 more. Subscribe to see the full list

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