Lambert Eaton myasthenic syndrome (LEMS): cancer management
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Lambert Eaton myasthenic syndrome (LEMS): cancer management. Computed tomography (CT) scan chest. Fully referenced neurology checklist.
Investigations for cancer
- Computed tomography (CT) scan chest
- Positron emission tomography (PET) scan: if CT is negative
- Also see Neurochecklist: “Paraneoplastic neurological syndromes: cancer screening”
Paraneoplastic risk assessment
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DELTA-P scoring items
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DELTA-P based cancer screening strategy items
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References
- Titulaer MJ, Lang B, Verschuuren JJGM. Lambert-Eaton myasthenic syndrome: from clinical characteristics to therapeutic strategies. Lancet 2011; 10:1098-1107.
- Sabater L, Titulaer M, Saiz A, Verschuuren J, Gure AO, Graus F. SOX1 antibodies are makers of paraneoplastic Lambert-Eaton myasthenic syndrome. Neurology 2008; 70:924-928.
- Titulaer MJ, Maddison P, Sont JK, et al. Clinical Dutch-English Lambert-Eaton mutagenic syndrome (LEMS) tumour association score accurately predicts small-cell lung cancer in the LEMS. J Clin Oncol 2011; 29:902-908.
- Weimer MB, Wong J. Lambert-eaton myasthenic syndrome. Curr Treat Options Neurol 2009; 11:77-84.
- Kesner VG, Oh SJ, Dimachkie MM, Barohn RJ. Lambert-Eaton myasthenic syndrome. Neurol Clin 2018; 36:379-394.
