Lyme neuroborreliosis: clinical features
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Lyme neuroborreliosis: clinical features. Tick bite: this is recalled in 40% of cases, Erythema migrans. Fully referenced neurology checklist.
Onset features
- Tick bite: this is recalled in 40% of cases
- Erythema migrans
- Lymphocytoma
Lymphocytic meningitis
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Cranial neuropathies
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Peripheral nerve features
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Cerebral vasculitis
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Other features
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References
- Mygland A, Ljosrad U, Fingerle V, Rupprecht T, Schmutzhard E, Steiner I. EFNS guidelines on the diagnosis and management of European Lyme neuroborreliosis. Eur J Neurol 2010; 17:8-16.
- Prasad A, Sankar D. Overdiagnosis and overtreatment of Lyme neuroborreliosis are preventable. Postgrad Med J 1999; 75:650-656.
- Gu K, Boodman C, Orr P, Wuerz T. Early Lyme neuroborreliosis manifesting as brachial plexopathy and meningitis in Northwestern Ontario, Canada: a case report. Medicine (Baltimore) 2022; 101:e31576.
- Bajons D, Fröhlich R, Grandits W, Krstic M, Rauschka H, Katzenschlager R. Lyme neuroborreliosis: Progressive cerebral vasculitis responsive to cyclophosphamide. A case report and review of the literature. J Stroke Cerebrovasc Dis 2023 (Online ahead of print).
- Winter Y, Simon OJ, Spreer A, et al. Cerebral vasculitis as clinical manifestation of neuroborreliosis: pattern of vascular pathology and prognostic factors of outcome. Int J Stroke 2025; 20:205-214.
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