Meningiomas: risk factors

Evidence-based neurology checklist on meningiomas: risk factors: Major tumour syndromes Neurofibromatosis type 2 (NF2) Multiple endocrine neoplasia type 1 (MEN1) Copy number alterations (CNAs) Major cancer predisposition mutations Other cancer predisposition mutations Epigenomic alterations: DNA…

Major tumour syndromes

  • Neurofibromatosis type 2 (NF2)
  • Multiple endocrine neoplasia type 1 (MEN1)

Copy number alterations (CNAs)

Major cancer predisposition mutations

Other cancer predisposition mutations

Epigenomic alterations: DNA methylation

Epigenomic alterations: micro RNA

Hormonal risk factors

Environmental risk factors

References

  1. Wiemels J, Wrensch M, Claus EB. Epidemiology and etiology of meningioma. J Neurooncol 2010; 99:307-314.
  2. Rogers L, Barani I, Chamberlain M, et al. Meningiomas: knowledge base, treatment outcomes, and uncertainties. A RANO review. J Neurosurg 2015; 122:4-23.
  3. Nigim F, Wakimoto H, Kasper EM, Ackermans L, Temel Y. Emerging medical treatments for meningioma in the molecular era. Biomedicines 2018; 6(3) pii: E86. 
  4. Claus EB, Calvocoressi L, Bondy ML, Wrensch M, Wiemels JL, Schildkraut JM. Exogenous hormone use, reproductive factors, and risk of intracranial meningioma in females. J Neurosurg 2013; 118:649-656. 
  5. Suppiah S, Nassiri F, Bi WL, et al; International Consortium on Meningiomas. Molecular and translational advances in meningiomas. Neuro Oncol 2019; 21(Supplement_1):i4-i17.
  6. And 7 more. Subscribe to see the full list

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