Multifocal motor neuropathy (MMN): clinical features

Evidence-based neurology checklist on multifocal motor neuropathy (mmn): clinical features: Main clinical features Upper limb onset weakness Wrist drop Weak grip Foot drop Frequent cramps Twitching Differential finger extension weakness Cold paresis: weakness is worse in the cold Rarer clinical…

Main clinical features

  • Upper limb onset weakness
  • Wrist drop
  • Weak grip
  • Foot drop
  • Frequent cramps
  • Twitching
  • Differential finger extension weakness
  • Cold paresis: weakness is worse in the cold

Rarer clinical features

Reported MMN risk factors

Monofocal motor neuropathy variant

Differential diagnosis: motor neurone disease (MND)

Differential diagnosis: others

References

  1. Willison H, Mills K. Multifocal motor neuropathy. Pract Neurol 2002; 2:298-301.
  2. Van Asseldonk JTH, Franssen H, Van den Berg-Vos RM, et al. Multifocal motor neuropathy. Lancet Neurol 2005; 4:309-319.
  3. Rajabally YA. Multifocal motor neuropathy: review of a treatable immune mediated disorder. Postgrad Med J 2008; 84:287-292.
  4. Slee M, Selvan A, Donaghy M. Multifocal motor neuropathy: the diagnostic spectrum and response to treatment. Neurology 2007; 69:1680-1687.
  5. Ivanovski T, Miralles F. Differential weakness of finger extensor muscles: a clinical pattern of multifocal motor neuropathy. Muscle Nerve 2017; 55:433-437.
  6. And 20 more. Subscribe to see the full list

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