Neuropathic itch: causes

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Neuropathic itch: causes. Stroke, Trigeminal trophic syndrome, Multiple sclerosis (MS). Fully referenced neurology checklist.

Cerebral causes

  • Stroke
  • Trigeminal trophic syndrome
  • Multiple sclerosis (MS)
  • Familial Creutzfeldt-Jakob disease (CJD)
  • Posterior fossa tumours
  • Brainstem paraneoplastic syndrome
  • Traumatic brain injury (TBI)
  • Abscesses
  • Medullary or pontine syrinx

Spinal cord causes

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Radicular causes

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Neuropathic causes

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Genetics causes

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Other causes

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References

  1. Steinhoff M, Schmelz M, Szabó IL, Oaklander AL. Clinical presentation, management, and pathophysiology of neuropathic itch. Lancet Neurol 2018; 17:709-720.
  2. Oaklander AL. Neuropathic itch. Semin Cutan Med Surg 2011; 30:87-92. 
  3. Dhand A, Aminoff MJ. The neurology of itch. Brain 2014; 137:313-322.
  4. Poddar S, Mondal H, Podder I. Aetiology, pathogenesis and management of neuropathic itch: a narrative review with recent updates. Indian J Dermatol Venereol Leprol. 2023 (Online ahead of print). 
  5. Berger JR, Bensalem M, Dalmau J. A brainstem paraneoplastic syndrome associated with prostate cancer. JNNP 2009; 80:934-935. 
  6. And 4 more. Subscribe to see the full list

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