Neuropsychiatric systemic lupus erythematosus (NPSLE): clinical features

Evidence-based neurology checklist on neuropsychiatric systemic lupus erythematosus (npsle): clinical features: Cerebral features Headache Seizures Acute confusional state Cerebrovascular disease Cognitive dysfunction Inflammatory and immune features Psychiatric features Peripheral features…

Cerebral features

  • Headache
  • Seizures
  • Acute confusional state
  • Cerebrovascular disease
  • Cognitive dysfunction

Inflammatory and immune features

Psychiatric features

Peripheral features

Differential diagnosis

References

  1. Zhou HQ, Zhang FC, Tian XP, et al. Clinical features and outcome of neuropsychiatric lupus in Chinese: analysis of 240 hospitalized patients. Lupus 2008; 17:93-99.
  2. Jain S, Khormi A, Sangle SR, D’Cruz DP. Transverse myelitis associated with systemic lupus erythematosus (SLE-TM): a review article. Lupus 2023; 32:1033-1042.
  3. Raciborska DD, Noyce AJ, Pyne D, Turner BP. Lupus myelopathy. Pract Neurol 2018; 18:66-69. 
  4. Budhram A, Butendieck RR, Duarte-Garcia A, Brinjikji W, Zalewski NL. Striatal encephalitis: potential inflammatory vasculopathy in systemic lupus erythematosus. Can J Neurol Sci 2020 (Online ahead of print).
  5. Munhoz RP, Fameli H, Teive HA. Stiff person syndrome as the initial manifestation of systemic lupus erythematosus. Mov Disord 2010; 25:516-517.
  6. And 10 more. Subscribe to see the full list

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