Parkinson's disease (PD): premotor features

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Parkinson's disease (PD): premotor features. Olfactory dysfunction, REM sleep behaviour disorder (RBD), Constipation. Fully referenced neurology checklist.

Highly predictive frequent PD premotor features

  • Olfactory dysfunction
  • REM sleep behaviour disorder (RBD)
  • Constipation

Other frequent PD premotor features

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Other PD premotor features

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Possible premotor PD features

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Subtle motor features in early PD

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References

  1. Siderowf A, Lang AE. Premotor Parkinson's disease: concepts and definitions. Mov Disord 2012; 27:608-616.
  2. Savica R, Rocca WA, Ahlskog JE. When does Parkinson disease start? Arch Neurol 2010; 67:798-801.
  3. Postuma RB, Aarsland D, Barone P, et al. Identifying prodromal Parkinson's disease: pre-motor disorders in Parkinson's disease. Mov Disord 2012; 27:617-626.
  4. Tolosa E, Gaig C, Santamaria J, Compta Y. Diagnosis and the premotor phase of Parkinson disease. Neurology 2009; 72(Suppl 2):S12-S20.
  5. Noyce AJ, Lees AJ, Schrag AE. The prediagnostic phase of Parkinson's disease. JNNP 2016; 87:871-878.
  6. And 10 more. Subscribe to see the full list

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