Polyarteritis nodosa (PAN): management

Evidence-based neurology checklist on polyarteritis nodosa (pan): management: Routine blood tests Full blood count Urinalysis: for proteinuria and haematuria Erythrocyte sedimentation rate ESR) C‐reactive protein (CRP) Muscle enzymes Liver function tests Serum creatinine Blood cultures Viral tests…

Routine blood tests

  • Full blood count
  • Urinalysis: for proteinuria and haematuria
  • Erythrocyte sedimentation rate ESR)
  • C‐reactive protein (CRP)
  • Muscle enzymes
  • Liver function tests
  • Serum creatinine
  • Blood cultures

Viral tests

Autoimmune tests

Imaging tests

Conventional treatments

Emerging treatments

References

  1. Pagnoux C, Seror R, Henegar C, et al. Clinical features and outcomes in 348 patients with polyarteritis nodosa: a systematic retrospective study of patients diagnosed between 1963 and 2005 and entered into the French Vasculitis Study Group Database. Arthritis Rheum 2010; 62:616-626.
  2. Howard T, Ahmad K, Swanson JA, Misra S. Polyarteritis nodosa. Tech Vasc Interv Radiol 2014; 17:247-251.
  3. Capuozzo M, Ottaiano A, Nava E, Cascone S, Fico R, Iaffaioli RV, Cinque C. Etanercept induces remission of polyarteritis nodosa: a case report. Front Pharmacol 2014; 5:122.
  4. Akiyama M, Kaneko Y, Takeuchi T. Tocilizumab for the treatment of polyarteritis nodosa: a systematic literature review. Ann Rheum Dis 2020 (Online ahead of print).
  5. Watanabe K, Rajderkar DA, Modica RF. A case of polyarteritis nodosa associated with vertebral artery vasculitis treated successfully with tocilizumab and cyclophosphamide. Case Rep Pediatr 2016; 2016:7987081.
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