Primary central nervous system lymphoma (PCNSL): other investigations

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Primary central nervous system lymphoma (PCNSL): other investigations. The cytology is normal in >50%. Fully referenced neurology checklist.

Cerebrospinal fluid (CSF) analysis

  • The cytology is normal in >50%
  • β2 microglobulin may be positive
  • Polymerase chain reaction (PCR) may be positive for Epstein Barr virus (EBV)

Other imaging investigations

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Slit lamp examination

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Other investigations

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References

  1. Slone HW, Blake JJ, Shah R, Guttikonda S, Bourekas EC. CT and MRI findings of intracranial lymphoma. Am J Roentgenol 2005; 184:1679-1685.
  2. Gavrilovic IT, Abrey LE. Diagnosis and treatment of primary central nervous system lymphoma. Curr Oncol Rep 2005; 7:47-54.
  3. Kuker W, Nagele T, Korfel A, et al. Primary central nervous system lymphomas (PCNSL): MRI features at presentation in 100 patients. J Neuro Oncol 2005; 72:169-177.
  4. Schlegel U. Primary CNS lymphoma. Ther Adv Neurol Disord 2009; 2:93-104.

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