Primary progressive aphasia (PPA): semantic variant (svPPA)
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Primary progressive aphasia (PPA): semantic variant (svPPA). Left posterior fronto-insular atrophy. Fully referenced neurology checklist.
Pathological features
- Left posterior fronto-insular atrophy
- This causes loss of memory for words
Clinical features
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Associated features
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References
- Gorno-Tempini ML, Hillis AE, Weintraub S, et al. Classification of primary progressive aphasia and its variants. Neurology 2011; 76:1006-1014.
- Seelar H, Rohrer JD, Pijnenburg AL, Fox NC, van Swieten JC. Clinical, genetic and pathological heterogeneity of frontotemporal dementia: a review. JNNP 2011; 82:476-486.
- Chare L, Hodges JR, Leyton CE, et al. New criteria for frontotemporal dementia syndromes: clinical and pathological diagnostic implications. JNNP 2014; 85:866–871.
- Hodges JR, Patterson K. Semantic dementia: a unique clinicopathological syndrome. Lancet Neurol 2007; 6:1004-1014.
- Mahoney CJ, Rohrer JD, Goll JC, Fox NC, Rossor MN, Warren JD. Structural neuroanatomy of tinnitus and hyperacusis in semantic dementia. JNNP 2011; 82:1274-1278.
