Rheumatoid cerebral vasculitis

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Rheumatoid cerebral vasculitis. This usually develops in women seropositive for Rheumatoid arthritis. Fully referenced neurology checklist.

Demographic features

  • This usually develops in women seropositive for Rheumatoid arthritis
  • They usually have erosive arthritis and subcutaneous nodules

Clinical features

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Differential diagnosis: autoimmune vasculitides

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Differential diagnosis: others

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Magnetic resonance imaging MRI) brain

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Cerebrospinal fluid (CSF) analysis

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Brain biopsy

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Blood tests

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Treatment

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Alternative treatments

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References

  1. Kurne A, Karabudak R, Karadag O, et al. An unusual central nervous system involvement in rheumatoid arthritis: combination of pachymeningitis and cerebral vasculitis. Rheumatol Int 2009; 29:1349-1353.
  2. Caballol Pons N, Montalà N, Valverde J, Brell M, Ferrer I, Martínez-Yélamos S. Isolated cerebral vasculitis associated with rheumatoid arthritis. Joint Bone Spine 2010; 77:361-363.
  3. Mrabet D, Meddeb N, Ajlani H, Sahli H, Sellami S. Cerebral vasculitis in a patient with rheumatoid arthritis. Joint Bone Spine 2007; 74:201-204. 
  4. Rida MA, El Najjar M, Merashli M. Neurologic manifestations of rheumatoid arthritis: a case of cerebral vasculitis treated with rituximab. Arch Rheumatol 2018; 34:238-240. 
  5. Xiao Y, Yang J, Xia J, Liu Y, Huang Q, Feng J. Spinal subarachnoid haemorrhage secondary to spinal rheumatoid vasculitis: a case report. BMC Neurol 2021; 21:465.
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