Sudden unexpected death in epilepsy (SUDEP): subject-related risk factors
Evidence-based neurology checklist on sudden unexpected death in epilepsy (sudep): subject-related risk factors: Individual risk factors Adult age Male gender Duration of epilepsy >15 years Onset age of epilepsy <16 years Learning difficulty Obstructive sleep apnoea (OSA) Cardiac autonomic…
Individual risk factors
- Adult age
- Male gender
- Duration of epilepsy >15 years
- Onset age of epilepsy <16 years
- Learning difficulty
- Obstructive sleep apnoea (OSA)
- Cardiac autonomic dysfunction
- Short term heart rate variability (HRV)
Behavioural risk factors
Possible genetic risk mutations
Radiological risk features
References
- Harden C, Tomson T, Gloss D, et al. Practice guideline summary: Sudden unexpected death in epilepsy incidence rates and risk factors: Report of the Guideline Development, Dissemination, and Implementation Subcommittee of the American Academy of Neurology and the American Epilepsy Society. Neurology 2017; 88:1674-1680.
- Hesdorffer DC, Tomson T, Benn E, et al. Combined analysis of risk factors for SUDEP. Epilepsia 2011; 52:1150-1159.
- So EL, Bainbridge J, Buchhalter JR, et al. Report of the American Epilepsy Society and the Epilepsy Foundation Joint Task Force on sudden unexplained death in epilepsy. Epilepsia 2009; 50:917-922.
- Tomson T, Nashef L, Ryvlin P. Sudden unexpected death in epilepsy: current knowledge and future directions. Lancet Neurol 2008; 7:1021-1031.
- Lhatoo SD, Faulkner HJ, Dembny K, Trippick K, Johnson C, Bird JM. An electroclinical case-control study of sudden unexpected death in epilepsy. Ann Neurol 2010; 68:787-796.
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