Systemic sclerosis (SS): systemic features

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Systemic sclerosis (SS): systemic features. Skin atrophy, Peri-buccal rhagades, Telangiectasia, Sclerodactyly. Fully referenced neurology checklist.

Dermatological features

  • Skin atrophy
  • Peri-buccal rhagades
  • Telangiectasia
  • Sclerodactyly
  • Raynaud’s phenomenon
  • Localised scleroderma or en coup de sabre
  • Neurotropic ulceration

Oral features

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Ocular features

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Internal organ involvement

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Skeletal features

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Autoantibodies

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Synonym

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References

  1. Vincent C, Agard C, Barbarot S, et al. Orofacial manifestations of systemic sclerosis: A study of 30 consecutive patients. Rev Stomatol Chir Maxillofac 2010; 111:128-134. 
  2. Amaral TN, Marques Neto JF, Lapa AT, Peres FA, Guirau CR, Appenzeller S. Neurologic involvement in scleroderma en coup de sabre. Autoimmune Dis 2012; 2012:719685.
  3. Sant SM, Murphy GM. Neurotropic ulceration in systemic sclerosis. Clin Exp Dermatol 1994; 19:65-66.
  4. Lock G, Straub RH, Zeuner M, et al. Association of autonomic nervous dysfunction and esophageal dysmotility in systemic sclerosis. J Rheumatol 1998; 25:1330-1335.
  5. Hietarinta M, Lassila O, Hietaharju A. Association of anti-U1RNP- and anti-Scl-70-antibodies with neurological manifestations in systemic sclerosis (scleroderma). Scand J Rheumatol 1994; 23:64-67.
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