Tropical spastic paraparesis (TSP): treatment
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Tropical spastic paraparesis (TSP): treatment. IV pulsed Methylprednisolone for induction. Fully referenced neurology checklist.
Steroid treatment
- IV pulsed Methylprednisolone for induction
- Oral Prednisolone 5mg daily for progressive disease
Non-evidenced treatments
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Investigational treatments
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Synonym
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References
- Araujo A, Bangham CRM, Casseb J, et al. Management of HAM/TSP: systematic review and consensus-based recommendations 2019. Neurol Clin Pract 2021 (Online ahead of print).
- Oh U, Jacobson S. Treatment of HTLV-I-associated myelopathy / tropical spastic paraparesis: towards rational targeted therapy. Neurol Clin 2008; 26:781-797.
- Yoshida T, Nozuma S, Tanaka M, et al. Dimethyl fumarate as a promising therapeutic candidate for virus-associated myelopathy. Brain 2026; 149:2550-2560.
