Tyrosine kinase inhibitors (TKI): dasatinib
Evidence-based neurology checklist on tyrosine kinase inhibitors (tki): dasatinib: Neurological complications Demyelinating peripheral neuropathy: this is reversible Optic neuropathy Rhabdomyolysis Cognitive impairment Inclusion body myositis (IBM) Pulmonary complications Cardiovascular…
Neurological complications
- Demyelinating peripheral neuropathy: this is reversible
- Optic neuropathy
- Rhabdomyolysis
- Cognitive impairment
- Inclusion body myositis (IBM)
Pulmonary complications
Cardiovascular complications
Renal complications
Gastrointestinal complications
Dermatological complications
Haematological complications
Other complications
References
- Inoue H, Taji H, Yamada K, et al. Dasatinib-induced reversible demyelinating peripheral neuropathy and successful conversion to nilotinib in chronic myelogenous leukemia. Intern Med 2020; 59:2419-2421.
- Ishida T, Akagawa N, Miyata T, et al. Dasatinib-associated reversible demyelinating peripheral polyneuropathy in a case of chronic myeloid leukemia. Int J Hematol 2018; 107:373-377.
- Monge KS, Gálvez-Ruiz A, Alvárez-Carrón A, Quijada C, Matheu A. Optic neuropathy secondary to dasatinib in the treatment of a chronic myeloid leukemia case. Saudi J Ophthalmol 2015; 29:227-231.
- Joel Chandranesan AS, Master S, Antosz O, PeytonThomas B, Koshy N. Dasatinib-induced rhabdomyolysis in a 33-year-old patient with chronic myeloid leukemia. Case Rep Hematol 2018; 2018:2849869.
- Chamoun K, Rabinovich E, Baer L, Fastenau P, Lima M. A case of neurocognitive deficit strongly related to dasatinib therapy. Hematol Transfus Cell Ther 2020; 42:80-82.
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