Diaphragmatic paralysis: neurological causes

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Diaphragmatic paralysis: neurological causes. C1-C2 root lesions: these cause complete diaphragmatic paralysis. Fully referenced neurology checklist.

Radiculopathies

  • C1-C2 root lesions: these cause complete diaphragmatic paralysis
  • C3-C5 root lesions: these cause partial diaphragmatic paralysis

Spinal cord disorders

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Anterior horn cell (AHC) disorders

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Neuropathic causes

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Neuromuscular junction (NMJ) disorders

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Muscle causes

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References

  1. McCool FD, Tzelepis GE. Dysfunction of the diaphragm. N Engl J Med 2012; 366:932-942.
  2. Gibson GJ. Diaphragmatic paresis: pathophysiology, clinical features, and investigation. Thorax 1989; 44:960-970.
  3. Crausman RS, Summerhill EM, McFool FD. Idiopathic diaphragmatic paralysis: Bell's palsy of the diaphragm. Lung 2009; 187:153-157.
  4. Matsumoto H, Nakayama T, Hamaguchi H, et al. Diaphragmatic paralysis in a patient with spinal cord infarction. Intern Med 2009; 48:1763-1766.
  5. Billings ME, Aitken ML, Benditt JO. Bilateral diaphragm paralysis: a challenging diagnosis. Respiratory Care 2008; 53:1368-1371.
  6. And 9 more. Subscribe to see the full list

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