Ciclosporine

Evidence-based neurology checklist on ciclosporine: Baseline assessments Full blood count (FBC) Renal function tests: this must be normal on two occasions Liver function test (LFT) Blood pressure (BP): this should be <140/90 mmHg on two occasions 2 weeks apart Fasting lipids Dosing Monitoring…

Baseline assessments

  • Full blood count (FBC)
  • Renal function tests: this must be normal on two occasions
  • Liver function test (LFT)
  • Blood pressure (BP): this should be <140/90 mmHg on two occasions 2 weeks apart
  • Fasting lipids

Dosing

Monitoring blood tests

Monitoring frequency

Contraindications

Precautions

Things to avoid

Complications

Indications for withholding Ciclosporin

Synonym

References

  1. Chakravarty K, McDonald H, Pullar T, et al. BSR/BHPR guideline for disease-modifying anti-rheumatic drug (DMARD) therapy in consultation with the British Association of Dermatologists. Rheumatology 2008; 47:924-925.
  2. Ledingham J, Gullick N, Irving K, et al. BSR and BHPR guideline for the prescription and monitoring of non-biologic disease-modifying anti-rheumatic drugs. Rheumatology (Oxford) 2017; 56:865-868.
  3. British Society of Rheumatology. National guidelines for the monitoring of second line drugs. July 2000.
  4. Sayin R, Soyoral YU, Erkoc R. Polyneuropathy due to cyclosporine A in patients with renal transplantation: a case report. Ren Fail 2011; 33:528-530. 
  5. Garrouste C, Philipponnet C, Kaysi S, Enache I, Tiple A, Heng AE. Severe colchicine intoxication in a renal transplant recipient on cyclosporine. Transplant Proc 2012; 44:2851-2852.
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