Creutzfeldt Jakob disease (CJD): investigations
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Creutzfeldt Jakob disease (CJD): investigations. These are in the caudate, putamen or cortical regions. Fully referenced neurology checklist.
Magnetic resonance imaging (MRI): high signal changes
- These are in the caudate, putamen or cortical regions
- These are mainly near the midline
- They have also been reported in the globus pallidus
Magnetic resonance imaging (MRI): cortical ribbon sign
Locked: subscribe to see this section.
Magnetic resonance imaging (MRI): other changes
Locked: subscribe to see this section.
Magnetic resonance spectroscopy (MRS)
Locked: subscribe to see this section.
Cerebrospinal fluid (CSF): routine indices
Locked: subscribe to see this section.
Cerebrospinal fluid (CSF): specific indices
Locked: subscribe to see this section.
Electroencephalogram (EEG)
Locked: subscribe to see this section.
Skin biopsy
Locked: subscribe to see this section.
Synonym
Locked: subscribe to see this section.
References
- Mahillo-Fernandez I, de Pedro-Cuesta J, Bleda MJ, et al. Surgery and risk of sporadic Creutzfeldt-Jakob disease in Denmark and Sweden: registry-based case-control study. Neuroepidemiology 2008; 31:229-240.
- Tschampa HJ, Kallenberg K, Kretzschmar HA, et al. Pattern of cortical changes in sporadic Creutzfeldt-Jakob disease. AJNR 2007; 28:1114-1118.
- de Priester JA, Jansen GH, de Kruijk JR, Wilmink JT. New MRI findings in Creutzfeldt-Jakob disease: high signal in the globus pallidus on T1-weighted images. Neuroradiology 1999; 41:265-268.
- Chen Z, Kong Y, Wu L. Punctate diffuse cortex signals in Creutzfeldt-Jakob disease. JAMA Neurol 2024; 81:291-292.
- Yasuda M, Sugiyama A, Hokkoku H, et al. Propagation of diffusion-weighted MRI abnormalities in the preclinical stage of sporadic Creutzfeldt-Jakob Disease. Neurology 2022; 99:699-702.
- And 14 more. Subscribe to see the full list
