Ischaemic stroke: predictors of mortality

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Ischaemic stroke: predictors of mortality. Older age, Female sex, White matter lesions (WML). Fully referenced neurology checklist.

General predictors

  • Older age
  • Female sex
  • White matter lesions (WML)
  • Elevated total homocysteine
  • Poor modified Rankin score
  • Possibly urinary incontinence
  • Ambient particulate matter

Cardiovascular predictors

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SOAR prediction score of long-term mortality

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References

  1. Oksala NKJ, Oksala A, Pohjasvaara T, et al. Age related white matter changes predict stroke death in long term follow up. JNNP 2009; 80:762-766.
  2. Tanaka M, Nakayama Y, Maeda Y, Nidhioka T, Shirakawa M, Tsumura K. Electrocardiographic-Q waves as a predictor of mortality in patients with cerebral infarction. Neurology 2004; 62:1818-1821.
  3. Shi Z, Guan Y, Huo YR, Liu S, Zhang M, Lu H, Yue W, Wang J, Ji Y. Elevated total homocysteine levels in acute ischemic stroke are associated with long-term mortality. Stroke 2015; 46:2419-2425. 
  4. John G, Bardini C, Mégevand P, Combescure C, Dällenbach P. Urinary incontinence as a predictor of death after new-onset stroke: a meta-analysis. Eur J Neurol 2016; 23:1548-1555.
  5. Cai M, Zhang S, Lin X, et al. Association of ambient particulate matter pollution of different sizes with in-hospital case fatality among stroke patients in China. Neurology 2022 (Online ahead of print).
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