Progressive supranuclear palsy (PSP): clinical features
Evidence-based neurology checklist on progressive supranuclear palsy (psp): clinical features: Core clinical domains Oculomotor dysfunction Postural instability Akinesia Cognitive dysfunction Facial features Ophthalmic features Postural and gait abnormalities Bulbar features Applause sign Postural…
Core clinical domains
- Oculomotor dysfunction
- Postural instability
- Akinesia
- Cognitive dysfunction
Facial features
Ophthalmic features
Postural and gait abnormalities
Bulbar features
Applause sign
Postural signs
Speech impairments
Other features
Poor prognostic markers
References
- Williams DR, Lees AJ. Progressive supranuclear palsy: clinicopathological concepts and diagnostic challenges. Lancet Neurol 2009; 8:270-279.
- Litvan I, Agid A, Calne D, et al. Clinical research criteria for the diagnosis of progressive supranuclear palsy (Steele-Richardson-Olszewski syndrome): report of the NINDS-PSP International Workshop. Neurology 1996; 47:1-9.
- Brazis PW, Masdeu JC, Biller J. Localization in Clinical Neurology. Lippincott Williams & Wilkins Philadelphia 2007 p445.
- Rojo A, Pernaute RS, Fontan A, et al. Clinical genetics of familial progressive supranuclear palsy. Brain 1999; 122:1233-1245.
- Höglinger GU, Respondek G, Stamelou M, et al; Movement Disorder Society-endorsed PSP Study Group. Clinical diagnosis of progressive supranuclear palsy: The movement disorder society criteria. Mov Disord 2017; 32:853-864.
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