Rhombencephalitis

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Rhombencephalitis. This is inflammation of the brainstem and cerebellum. It is confirmed on brain imaging. Fully referenced neurology checklist.

Pathology

  • This is inflammation of the brainstem and cerebellum
  • It is confirmed on brain imaging
  • It is associated with cerebrospinal fluid (CSF) pleocytosis >4cells/mm

Viral causes

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Other infective causes

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Inflammatory causes

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Autoimmune causes

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Paraneoplastic causes

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Other causes

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Clinical features

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Differential diagnosis

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Magnetic resonance imaging (MRI) brain

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Investigations

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Treatment

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Synonym

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Acronyms

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References

  1. Cleaver J, James R, Rice CM. Rhomboencephalitis. Pract Neurol 2020 (Online ahead of print).
  2. Jubelt B, Mihai C, Li TM, Veerapaneni P. Rhombencephalitis / brainstem encephalitis. Curr Neurol Neurosci Rep 2011; 11:543-552.
  3. Campos LG, Trindade RA, Faistauer Â, Pérez JA, Vedolin LM, Duarte JÁ. Rhombencephalitis: pictorial essay. Radiol Bras 2016; 49:329-336.
  4. Moragas M, Martínez-Yélamos S, Majós C, Fernández-Viladrich P, Rubio F, Arbizu T. Rhombencephalitis: a series of 97 patients. Medicine (Baltimore) 2011; 90:256-261.
  5. Jeanneret V, Winkel D, Risman A, Shi H, Gombolay G. Post-infectious rhombencephalitis after coronavirus-19 infection: A case report and literature review. J Neuroimmunol 2021; 357:577623.
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