Sickle cell disease (SCD): stroke treatment

Evidence-based neurology checklist on sickle cell disease (scd): stroke treatment: Acute stroke treatment Thrombolysis: this is safe and effective Multidisciplinary care Stroke rehabilitation Primary stroke prevention Secondary stroke prevention Investigational secondary stroke prevention:…

Acute stroke treatment

  • Thrombolysis: this is safe and effective
  • Multidisciplinary care
  • Stroke rehabilitation

Primary stroke prevention

Secondary stroke prevention

Investigational secondary stroke prevention: antiplatelets

References

  1. Brousse V, Kossorotoff M, de Montalembert M. How I manage cerebral vasculopathy in children with sickle cell disease. Br J Haematol 2015; 170:615-625. 
  2. Yawn BP, Buchanan GR, Afenyi-Annan AN, et al. Management of sickle cell disease: summary of the 2014 evidence-based report by expert panel members. JAMA 2014; 312:1033-1048.
  3. Kassim AA, Galadanci NA, Pruthi S, DeBaun MR. How I treat and manage strokes in sickle cell disease. Blood 2015; 125:3401-3410.
  4. Sheehan VA, Hansbury EN, Smeltzer MP, Fortner G, McCarville MB, Aygun B. Transcranial Doppler velocity and brain MRI/MRA changes in children with sickle cell anemia on chronic transfusions to prevent primary stroke. Pediatr Blood Cancer 2013; 60:1499-1502.
  5. DeBaun MR, Gordon M, McKinstry RC, et al. Controlled trial of transfusions for silent cerebral infarcts in sickle cell anemia. N Engl J Med 2014; 371:699-710. 
  6. And 3 more. Subscribe to see the full list

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