Sporadic fatal insomnia (SFI): clinical features
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Sporadic fatal insomnia (SFI): clinical features. The mean onset age is 43 years. Fully referenced neurology checklist.
Demographic features
- The mean onset age is 43 years
- The mean disease duration is 30 months
Sleep disorders
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Cognitive features
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Clinical features
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Bulbar features
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Other features
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Comparison with fatal familial insomnia
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Synonym
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References
- Abu-Rumeileh S, Redaelli V, Baiardi S, et al. Sporadic fatal insomnia in Europe: phenotypic features and diagnostic challenges. Ann Neurol 2018; 84:347-360.
- Moody KM, Schonberger LB, Maddox RA, Zou WQ, Cracco L, Cali I. Sporadic fatal insomnia in a young woman: a diagnostic challenge: case report. BMC Neurol 2011; 11:136.
- Mkhitarjan T, Areškevičiūtė A, Lund EL, Marner L, Hejl AM. Sporadic fatal insomnia presenting with initial symptoms of parkinsonism and abnormal dopamine transporter imaging. Mov Disord Clin Pract 2021; 9:249-251.
- Tabaee Damavandi P, Dove MT, Pickersgill RW. A review of drug therapy for sporadic fatal insomnia. Prion 2017; 11:293-299.
- Chen Z, Chu M, Zhang J, et al. Clinical profiles and ethnic heterogeneity of sporadic fatal insomnia. Eur J Neurol 2023; 30:813-822.
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